Peritoneal Mesothelioma

Peritoneal Mesothelioma is the second-most prevalent form of asbestos-related cancer, rarer than the pleural variety, and accounting for about 10% - 15% of all diagnosed Mesothelioma cases. This form of cancer affects the lining of the abdomen, known as the peritoneum.

Doctors and researchers offer two theories as to how asbestos fibers are able to enter the peritoneum. Some believe that the fibers are caught and held by the mucus in the trachea or bronchi and ultimately swallowed. The second explanation notes that fibers lodged in the lungs may move into the lymphatic system and be transferred to the peritoneum.

Regardless of which explanation is correct, peritoneal Mesothelioma can be quite difficult to detect, as the cancer may lay dormant for many years. Like all types of asbestos-related cancers, documented incidences show that this type has, at times, been dormant for up to four decades. That, of course, makes it all the more difficult to treat this disease because, by the time it’s detected, it has reached its advanced stages.

The symptoms of peritoneal Mesothelioma are non-specific and can often be mistaken as indicators of a much less serious disease. Therefore, it’s important to let medical professionals know that the patient has been exposed to asbestos in the past. Symptoms of this type of Mesothelioma might include:

• Abdominal pain
• Abdominal swelling due to fluid accumulation
• Weight loss
• Loss of appetite
• Weakness
• Nausea
• Bowel obstruction
• Breathing difficulties

Location of the tumor will determine which symptoms are present and/or most severe and symptoms may be different according to the patient’s general health and age.

Often, the diagnosis of peritoneal Mesothelioma is accidental, perhaps discovered during an x-ray for another ailment. Additional x-rays, CT scans, or MRIs may be ordered but, ultimately, a tissue biopsy will be the most conclusive test.

Once this type of Mesothelioma is diagnosed, treatment options will be discussed. While there is currently no cure for this disease, the patient can be treated in a variety of ways to help ease symptoms, reduce pain, and prolong life. Options include:

• Surgery – the surgery performed for peritoneal Mesothelioma may involve cutting out part of the lining and tissue from the abdominal area in order to remove the tumor. If the tumor is particularly large, a lung or a section of the diaphragm may need to be removed as well. Because this type of cancer is so often diagnosed in its late stages, surgery may not be an option as the cancer has already spread too much by this point.
• Chemotherapy – the use of intra-peritoneal chemotherapy is often recommended to patients with peritoneal Mesothelioma. This involves the infusion of chemotherapy drugs directly into the abdominal cavity. It can be used after surgery or on its own.
• Radiation therapy – radiation may be targeted directly at cancer cells or can be used for palliative reasons such as to reduce pain or shortness of breath or to control the spread of the tumor.
• Clinical trials – some patients choose to participate in clinical trials or employ the use of therapies that have not yet been deemed successful in treating the disease, such as gene therapy or immunotherapy.

Although peritoneal Mesothelioma is not the most prevalent form of asbestos-related cancer, it is indeed a serious problem and many people die each year from the disease. If you, a friend, or a loved one has been diagnosed with this or any other type of asbestos-related cancer, learn about your options and rights by ordering our free Mesothelioma Resource Kit, full of information on the disease, its treatments, and the legal options of an asbestos-related cancer victim.

Pleural Mesothelioma

There are two types of Pleural Mesothelioma: Cancerous and non-cancerous.

Benign mesothelioma many times can be surgically removed and is generally not life threatening or a result of asbestos exposure. Malignant mesothelioma is very serious, though. The infliction is quite rare and less than three thousand people in the US get it each year.

The following section is about malignant pleural mesothelioma:

Pleural mesothelioma is a cancer of the cells that affects the skin or inner lining (known medically as the pleura) outside of the lungs and inside of the ribs. This is caused ONLY by exposure to asbestos fibers found in products made mostly by US corporations. The exposure could have occurred many, many years ago because it takes many years for the disease to show up. Pleural mesothelioma is the most common type of mesothelioma and chances are that if you have mesothelioma, this is the type you have.

Often Mesothelioma is diagnosed when no symptoms are present. This could be because a tumor is present or is randomly discovered through something like a routine exam. When these symptoms do occur, they can include shortness of breath, weight loss, chest pains, pains about the lower back, chronic cough, difficulty swallowing, and severe weakness. In the initial examination a medical examination will often show a pleural effusion, which is a bunch of fluid in the area between the lungs and the wall of the chest.

A chest x-ray or CT scan is the necessary first step in identifying mesothelioma, which is followed up with what is called a bronchoscopy. A bronchoscopy requires a viewing scope to look inside the lungs. The diagnosis itself requires a biopsy which allows the medical professionals to take a little piece of tissue from the area in question. This can be done using a tiny needle, an open cut, or even these days through a tube with a camera on the end of it. This is a procedure that must happen at the hospital, but it is not a painful procedure typically.

Any fluid build-up from the pleural effusion can generally be viewed via the x-ray and can be heard through the dr.’s stethoscope during examination. The only firm diagnosis of mesothelioma can be made through the biopsy described earlier. Because other things like tumors and benign effusions can look like mesothelioma, a biopsy is the only safe way to tell as a diagnosis of mesothelioma can be one of the most difficult in the book.

As the tumor spreads over the lining between the lungs and the chest, flexibility can be increasingly painful and restricted. Because of this, breathing becomes much more difficult. It begins with shortness of breath potentially while exercising but as function continues to drop short breath can become more and more of a persistent problem.

Although there is no cure for pleural mesothelioma, the treatment options have improved for managing symptoms. As with any cancer, the prognosis is better for those diagnosed early, and treatment can be more aggressive. Most pleural mesothelioma patients are treated with a multimodal therapy, or combination of treatment options. It is possible for patients with pleural mesothelioma to live for 5 to 10 years after diagnosis, although the average survival time is about a year.

Specific types of treatment include:

• Chemotherapy and other drug-based therapies
• Radiation therapy
• Surgery
• Intra-operative photodynamic therapy.

Experimental treatments such as gene therapy, angiogenesis inhibitors, immunotherapy, and many clinical trials are also in the development stages.

Although mesothelioma remains uncurable, many other treatments have had success in pain reduction and improving lung function. Surgeries to remove tumors and reduce pressure have shown promise in pain reduction, and pain control medications are constantly improving. In some cases, X-ray therapy has been shown to control tumor pain as well

Hidden asbestos risks

The risk of developing mesothelioma is not just confined to the person directly exposed but may extend to family members and friends of those directly exposed. Even someone who has not been directly exposed or has been exposed at very low levels is at risk may develop the disease.

An increasing incidence of mesothelioma in spouses and children whose only to asbestos was from the dust laden work clothes of a family member is being reported. People who were in contact with workers in asbestos related injuries should also be vigilant for symptoms and be screened for lung disorders regularly.

Asbestos exposure

The most common way in which people are exposed to asbestos is through their work. There are a number of jobs in which exposure to asbestos may have occurred. Asbestos has been extensively used in industrial products, including cement, brake linings, roof shingles, flooring products, textiles, and insulation as well as shipbuilding and other forms of construction. The risk of developing Mesothelioma increases according to the length and level of exposure to asbestos.

The number of workers exposed to asbestos far exceeds the number of documented cases. The reasons why some people who are exposed to asbestos do not develop the disease are not well understood.

The risk of developing asbestos-related diseases varies with the type of industry in which the exposure occurred and with the extent of the exposure. According to the Environmental Protection Agency (EPA) there is no safe level of exposure to asbestos fibers. The Occupational Safety and Health Administration (OSHA), however, has set a Permissible Exposure Limit (PEL) of 0.1 fibers per cubic centimeter (f/cc) for an 8 hour time weighted average. The safest course of action is to limit exposure and always wear protective gear when dealing with any type of suspected asbestos.

Mesothelioma Risk Factors

n as many as 75-85% of mesothelioma cases, there is a history of exposure to asbestos. The material was used extensively in numerous industries from the early 1900’s through the 1960’s. Through the World War II era, over 8 million workers were exposed to asbestos. Evidence that serious health problems were related to asbestos began to mount, and in 1999, a conclusive link between asbestos exposure and mesothelioma was made.

Because it can take as long as 50 years for mesothelioma to develop, anyone who has been exposed should be evaluated by a physician experienced in this form of cancer. Even if you are not ill, you should learn about your legal rights in case mesothelioma is found in the future.

Asbestos is a broad term which refers to a collection of minerals know as asbestiform. It is a small mineral comprised of tiny fibers. Asbestos fibers exist in two forms; they can be either amphibole or serpentine (chrysotile). Several studies suggest that the amphibole form of asbestos is more dangerous than the chrysotile form, especially in mesothelioma.

These small particles float in the air, in an exposed environment and they may be inhaled or swallowed. Asbestos fibers breathed into the lungs cannot be expelled; they become embedded in the thin lining of the lungs, the mesothelium. Over the period of many years, cells in the mesothelium can become cancerous. In most cases of mesothelioma, it takes decades for the disease to cause symptoms.

Although a serious hazard to your health, asbestos is an excellent insulating material. It is used in many products that need to withstand high heat such as home insulation and construction, brake pads, electrical equipment, hot water piping, boilers, ship engines, and welding supplies. People who have worked in these industries should be screened regularly for the development of lung disease.

When the asbestos is contained within finished products such as walls and tiles, it does not appear to pose a health as long as it is not damaged or disturbed. However, damage or inadvertent destruction can release dangerous fibers into the air. When asbestos fibers are set free and inhaled, however, exposed individuals are at risk of developing an asbestos-related disease.

While smoking has not been found to cause mesothelioma, smoking has been linked to an increased incidence in mesothelioma in asbestos exposed workers. Therefore, if you have had occupational e exposure to asbestos, smoking could raise the risk of developing mesothelioma.